Cargando…
Antiproliferative Activity of Crocin Involves Targeting of Microtubules in Breast Cancer Cells
Crocin, a component of saffron spice, is known to have an anticancer activity. However, the targets of crocin are not known. In this study, crocin was found to inhibit the proliferation of HCC70, HCC1806, HeLa and CCD1059sk cells by targeting microtubules. Crocin depolymerized both the interphase an...
Autores principales: | Hire, Rupali R., Srivastava, Shalini, Davis, Melissa B., Kumar Konreddy, Ananda, Panda, Dulal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364484/ https://www.ncbi.nlm.nih.gov/pubmed/28337976 http://dx.doi.org/10.1038/srep44984 |
Ejemplares similares
-
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy
por: Kapoor, Sonia, et al.
Publicado: (2018) -
Methyl-β-cyclodextrin, an actin depolymerizer augments the antiproliferative potential of microtubule-targeting agents
por: Mundhara, Nikita, et al.
Publicado: (2019) -
C1, a highly potent novel curcumin derivative, binds to tubulin, disrupts microtubule network and induces apoptosis
por: Srivastava, Shalini, et al.
Publicado: (2016) -
The Effect of the Crocus Sativus L. Carotenoid, Crocin, on the Polymerization of Microtubules, in Vitro
por: Zarei Jaliani, Hossein, et al.
Publicado: (2013) -
Crocin Bleaching Assay Using Purified Di-gentiobiosyl Crocin (-crocin) from Iranian Saffron
por: Bathaie, Seyedeh Zahra, et al.
Publicado: (2011)