Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway

Resveratrol, an edible polyphenolic phytoalexin, improves endothelial dysfunction and attenuates inflammation. However, the mechanisms have not been thoroughly elucidated. Therefore, we investigated the molecular basis of the effects of resveratrol on TNF-α-induced ICAM-1 expression in HUVECs. The r...

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Detalles Bibliográficos
Autores principales: Liu, Chen-Wei, Sung, Hsin-Ching, Lin, Shu-Rung, Wu, Chun-Wei, Lee, Chiang-Wen, Lee, I.-Ta, Yang, Yi-Fan, Yu, I-Shing, Lin, Shu-Wha, Chiang, Ming-Hsien, Liang, Chan-Jung, Chen, Yuh-Lien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364502/
https://www.ncbi.nlm.nih.gov/pubmed/28338009
http://dx.doi.org/10.1038/srep44689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364502/
https://www.ncbi.nlm.nih.gov/pubmed/28338009
http://dx.doi.org/10.1038/srep44689

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