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Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway
Resveratrol, an edible polyphenolic phytoalexin, improves endothelial dysfunction and attenuates inflammation. However, the mechanisms have not been thoroughly elucidated. Therefore, we investigated the molecular basis of the effects of resveratrol on TNF-α-induced ICAM-1 expression in HUVECs. The r...
Autores principales: | Liu, Chen-Wei, Sung, Hsin-Ching, Lin, Shu-Rung, Wu, Chun-Wei, Lee, Chiang-Wen, Lee, I.-Ta, Yang, Yi-Fan, Yu, I-Shing, Lin, Shu-Wha, Chiang, Ming-Hsien, Liang, Chan-Jung, Chen, Yuh-Lien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364502/ https://www.ncbi.nlm.nih.gov/pubmed/28338009 http://dx.doi.org/10.1038/srep44689 |
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