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Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
BACKGROUND: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not been explored. RESULTS: To investigate the occurrence of DNA methylation changes...
Autores principales: | Maag, Jesper L. V., Kaczorowski, Dominik C., Panja, Debabrata, Peters, Timothy J., Bramham, Clive R., Wibrand, Karin, Dinger, Marcel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364592/ https://www.ncbi.nlm.nih.gov/pubmed/28335720 http://dx.doi.org/10.1186/s12864-017-3621-x |
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