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Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(−/−) mice may be associated with increased PCSK9 expression

Hyperlipidemia is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a lipid regulatory gene involved in cell apoptosis. However, the function and mechanism of PCSK9 in neuronal apoptosis following hyperlipid...

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Detalles Bibliográficos
Autores principales:	Zhao, Xue-Shan, Wu, Qi, Peng, Juan, Pan, Li-Hong, Ren, Zhong, Liu, Hui-Ting, Jiang, Zhi-Sheng, Wang, Gui-Xue, Tang, Zhi-Han, Liu, Lu-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364825/ https://www.ncbi.nlm.nih.gov/pubmed/28000893 http://dx.doi.org/10.3892/mmr.2016.6055

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