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Safety and toxicology of the intravenous administration of Ang2-siRNA plasmid chitosan magnetic nanoparticles

This aim of the present study was to investigate the safety and toxicology of intravenous administration of angiopoietin-2 (Ang2)-small interfering (si)RNA plasmid-chitosan magnetic nanoparticles (CMNPs). Ang2-CMNPs were constructed and subsequently administered at different doses to mice and rats v...

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Detalles Bibliográficos
Autores principales:	Shan, Xiuying, Xu, Tingting, Liu, Zhaoliang, Hu, Xuefeng, Zhang, Yan-Ding, Wang, Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364838/ https://www.ncbi.nlm.nih.gov/pubmed/28035391 http://dx.doi.org/10.3892/mmr.2016.6090

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