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Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils

RNA interference has been considered as an effective gene silencing method in basic and preclinical investigations. The aims of the present study were to construct a lentiviral vector expressing a short hairpin RNA (shRNA) targeting the murine CC chemokine receptor 3 (mCCR3), and to investigate its...

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Detalles Bibliográficos
Autores principales: Zhu, Xin-Hua, Liao, Bing, Xu, Yi, Liu, Ke, Huang, Yun, Huang, Quan-Long, Liu, Yue-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364839/
https://www.ncbi.nlm.nih.gov/pubmed/28035394
http://dx.doi.org/10.3892/mmr.2016.6085

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