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Determining EGFR-TKI sensitivity of G719X and other uncommon EGFR mutations in non-small cell lung cancer: Perplexity and solution

Mutations in epidermal growth factor receptor (EGFR) play critical roles in the pathogenesis of non-small cell lung cancer (NSCLC), and they are highly associated with sensitivity to tyrosine kinase inhibitors (TKIs). While the pathogenic and pharmacological characteristics of common mutations in EG...

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Detalles Bibliográficos
Autores principales:	Li, Kaidi, Yang, Maojun, Liang, Naixin, Li, Shanqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364853/ https://www.ncbi.nlm.nih.gov/pubmed/28184913 http://dx.doi.org/10.3892/or.2017.5409

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