Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report

Implantation of carmustine-impregnated wafers (Gliadel(®)) into the tumor resection cavity has demonstrated a survival benefit for patients with malignant glioma. However, some precautions should be taken regarding Gliadel implantation. We report a case of a 63-year-old man with glioblastoma who was...

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Autores principales: Nakada, Mitsutoshi, Tanaka, Shingo, Oishi, Masahiro, Miyashita, Katsuyoshi, Misaki, Kouichi, Mohri, Masanao, Hayashi, Yasuhiko, Uchiyama, Naoyuki, Watanabe, Takuya, Hayashi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364932/
https://www.ncbi.nlm.nih.gov/pubmed/28663960
http://dx.doi.org/10.2176/nmccrj.2014-0080
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author Nakada, Mitsutoshi
Tanaka, Shingo
Oishi, Masahiro
Miyashita, Katsuyoshi
Misaki, Kouichi
Mohri, Masanao
Hayashi, Yasuhiko
Uchiyama, Naoyuki
Watanabe, Takuya
Hayashi, Yutaka
author_facet Nakada, Mitsutoshi
Tanaka, Shingo
Oishi, Masahiro
Miyashita, Katsuyoshi
Misaki, Kouichi
Mohri, Masanao
Hayashi, Yasuhiko
Uchiyama, Naoyuki
Watanabe, Takuya
Hayashi, Yutaka
author_sort Nakada, Mitsutoshi
collection PubMed
description Implantation of carmustine-impregnated wafers (Gliadel(®)) into the tumor resection cavity has demonstrated a survival benefit for patients with malignant glioma. However, some precautions should be taken regarding Gliadel implantation. We report a case of a 63-year-old man with glioblastoma who was implanted with Gliadel after a left temporal lobe tumor had been removed, and who later developed vasospasm of the lenticulostriate artery close to the implanted Gliadel, leading to serious cerebral infarction. Therefore, the implantation of Gliadel in cases where important vessels run close to the resection cavity should be considered with great caution.
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spelling pubmed-53649322017-06-29 Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report Nakada, Mitsutoshi Tanaka, Shingo Oishi, Masahiro Miyashita, Katsuyoshi Misaki, Kouichi Mohri, Masanao Hayashi, Yasuhiko Uchiyama, Naoyuki Watanabe, Takuya Hayashi, Yutaka NMC Case Rep J Case Report Implantation of carmustine-impregnated wafers (Gliadel(®)) into the tumor resection cavity has demonstrated a survival benefit for patients with malignant glioma. However, some precautions should be taken regarding Gliadel implantation. We report a case of a 63-year-old man with glioblastoma who was implanted with Gliadel after a left temporal lobe tumor had been removed, and who later developed vasospasm of the lenticulostriate artery close to the implanted Gliadel, leading to serious cerebral infarction. Therefore, the implantation of Gliadel in cases where important vessels run close to the resection cavity should be considered with great caution. The Japan Neurosurgical Society 2014-09-29 /pmc/articles/PMC5364932/ /pubmed/28663960 http://dx.doi.org/10.2176/nmccrj.2014-0080 Text en © 2015 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Nakada, Mitsutoshi
Tanaka, Shingo
Oishi, Masahiro
Miyashita, Katsuyoshi
Misaki, Kouichi
Mohri, Masanao
Hayashi, Yasuhiko
Uchiyama, Naoyuki
Watanabe, Takuya
Hayashi, Yutaka
Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title_full Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title_fullStr Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title_full_unstemmed Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title_short Cerebral Infarction Related to Carmustine Wafers in Glioblastoma: A Case Report
title_sort cerebral infarction related to carmustine wafers in glioblastoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364932/
https://www.ncbi.nlm.nih.gov/pubmed/28663960
http://dx.doi.org/10.2176/nmccrj.2014-0080
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