Cargando…

MicroRNA-185 regulates transforming growth factor-β1 and collagen-1 in hypertrophic scar fibroblasts

Transforming growth factor-β1 (TGF-β1) and collagen type I (Col-1) serve a critical role in the development and progression of hypertrophic scarring (HS). The present study hypothesized that a post-translational mechanism of microRNAs (miR) regulated the expression of TGF-β1 and Col-1 in HS fibrobla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Kaiyan, Luo, Xusong, Wang, Xiuxia, Gao, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364971/ https://www.ncbi.nlm.nih.gov/pubmed/28259900 http://dx.doi.org/10.3892/mmr.2017.6179

Ejemplares similares

MicroRNA-663 regulates the proliferation of fibroblasts in hypertrophic scars via transforming growth factor-β1
por: Chen, Qi, et al.
Publicado: (2018)

MicroRNA-222 regulates the viability of fibroblasts in hypertrophic scars via matrix metalloproteinase 1
por: Zhang, Yi, et al.
Publicado: (2018)

MicroRNA-21 Regulates hTERT via PTEN in Hypertrophic Scar Fibroblasts
por: Zhu, Hua-Yu, et al.
Publicado: (2014)

Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts
por: FAN, CHEN, et al.
Publicado: (2015)

MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1
por: Bi, Sheng, et al.
Publicado: (2017)

Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts
por: Zhang, Qing, et al.
Publicado: (2023)

USP15 Enhances the Proliferation, Migration, and Collagen Deposition of Hypertrophic Scar–Derived Fibroblasts by Deubiquitinating TGF-βR1 In Vitro
por: Tu, Longxiang, et al.
Publicado: (2021)

Effect of THBS1 on the Biological Function of Hypertrophic Scar Fibroblasts
por: Jiang, D., et al.
Publicado: (2020)

MicroRNA expression signature and the therapeutic effect of the microRNA-21 antagomir in hypertrophic scarring
por: Guo, Liang, et al.
Publicado: (2017)

MicroRNA 181b Regulates Decorin Production by Dermal Fibroblasts and May Be a Potential Therapy for Hypertrophic Scar
por: Kwan, Peter, et al.
Publicado: (2015)

MicroRNA-486-5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression
por: Shi, Yingying, et al.
Publicado: (2019)

Overexpression of miR-101 suppresses collagen synthesis by targeting EZH2 in hypertrophic scar fibroblasts
por: Li, Jie, et al.
Publicado: (2021)

Oxymatrine promotes hypertrophic scar repair through reduced human scar fibroblast viability, collagen and induced apoptosis via autophagy inhibition
por: Deng, Xingwang, et al.
Publicado: (2021)

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21
por: Liu, Ying, et al.
Publicado: (2016)

TGF-β1 upregulates Sar1a expression and induces procollagen-I secretion in hypertrophic scarring fibroblasts
por: Ahn, Keun Jae, et al.
Publicado: (2022)

MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting peroxisome proliferator-activated receptor β
por: Chai, Chi-Yung, et al.
Publicado: (2020)

Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts
por: Li, Shiyi, et al.
Publicado: (2022)

MicroRNA-182-5p Inhibits Hypertrophic Scar Formation by Inhibiting the Proliferation and Migration of Fibroblasts via SMAD4 Pathway
por: Jin, Mingzhu, et al.
Publicado: (2023)

miR-495 inhibits the growth of fibroblasts in hypertrophic scars
por: Guo, Bingyu, et al.
Publicado: (2019)

Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts
por: Zeng, Jian, et al.
Publicado: (2020)

Effects of Botulinum Toxin Type A on Collagen Deposition in Hypertrophic Scars
por: Xiao, Zhibo, et al.
Publicado: (2012)

Vascular and Collagen Target: A Rational Approach to Hypertrophic Scar Management
por: Yuan, Bo, et al.
Publicado: (2023)

Decreased expression of microRNA-145 promotes the biological functions of fibroblasts in hypertrophic scar tissues by upregulating the expression of transcription factor SOX-9
por: Wang, Shoujie, et al.
Publicado: (2019)

MicroRNA-365a/b-3p as a Potential Biomarker for Hypertrophic Scars
por: Lee, Joon Seok, et al.
Publicado: (2022)

Simultaneous silencing of TGF-β1 and COX-2 reduces human skin hypertrophic scar through activation of fibroblast apoptosis
por: Zhou, Jia, et al.
Publicado: (2017)

The inhibitory effects of 20(R)-ginsenoside Rg3 on the proliferation, angiogenesis, and collagen synthesis of hypertrophic scar derived fibroblasts in vitro
por: Tang, Mengyao, et al.
Publicado: (2018)

Topical cryoanesthesia for the relief of pain caused by steroid injections used to treat hypertrophic scars and keloids
por: Wang, Xiuxia, et al.
Publicado: (2017)

Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts
por: Raktoe, Rajiv S, et al.
Publicado: (2020)

Cuprous oxide nanoparticles reduces hypertrophic scarring by inducing fibroblast apoptosis
por: Xiao, Yongqiang, et al.
Publicado: (2019)

Abstract 3: Identification of Fibroblast Subtypes during Hypertrophic Scar Development
por: Kuehlmann, Britta, et al.
Publicado: (2017)

The Roles of microRNA miR-185 in Digestive Tract Cancers
por: Babaeenezhad, Esmaeel, et al.
Publicado: (2022)

The Effects of the Transforming Growth Factor-β1 (TGF-β1) Signaling Pathway on Cell Proliferation and Cell Migration are Mediated by Ubiquitin Specific Protease 4 (USP4) in Hypertrophic Scar Tissue and Primary Fibroblast Cultures
por: Huang, Yong, et al.
Publicado: (2020)

Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human Skin
por: Cui, Hui Song, et al.
Publicado: (2023)

Comparative proteomic analysis of extracellular matrix proteins secreted by hypertrophic scar with normal skin fibroblasts
por: Ma, Li, et al.
Publicado: (2014)

MicroRNA-499-5p inhibits transforming growth factor-β1-induced Smad2 signaling pathway and suppresses fibroblast proliferation and collagen synthesis in rat by targeting TGFβ-R1
por: Zhao, Qing, et al.
Publicado: (2023)

MicroRNA-185 oscillation controls circadian amplitude of mouse Cryptochrome 1 via translational regulation
por: Lee, Kyung-Ha, et al.
Publicado: (2013)

Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway
por: Zhao, Danyang, et al.
Publicado: (2017)

The combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars: An effective therapy for treating refractory keloids and hypertrophic scars
por: Luo, Quan‐Feng
Publicado: (2023)

sncRNA changes induced by tension in hypertrophic scar: sncRNAs in hypertrophic scar
por: Yin, Chuang, et al.
Publicado: (2022)

The Study on the Effect of Epidermal Growth Factor and Transforming Growth Factor-β1 in Intracellular Niche of Keloid Scar Fibroblast
por: Jae Lee, Sun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_19nfodgn5olq3fu88gkmb0dr8o