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miR-34a is downregulated in human osteosarcoma stem-like cells and promotes invasion, tumorigenic ability and self-renewal capacity

MicroRNA-34 (miR-34), in particular miR-34a, has a negative regulatory effect on osteosarcoma cell proliferation, migration and invasion. Notably, it is also a post-transcriptional regulatory factor of (sex determining region Y)-box 2 (Sox-2), which is required for osteosarcoma cell self-renewal and...

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Detalles Bibliográficos
Autores principales:	Zou, Yonggen, Huang, Yuanshuai, Yang, Jiexiang, Wu, Jian, Luo, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364984/ https://www.ncbi.nlm.nih.gov/pubmed/28260055 http://dx.doi.org/10.3892/mmr.2017.6187

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