Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

Actinobacteria produce a variety of polyketide alkaloids with unusual structures. Recently, it was shown that a type I modular polyketide synthase (PKS) is involved in the assembly of coelimycin P1, a polyketide alkaloid produced by Streptomyces coelicolor M145. However, the mechanisms for convertin...

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Detalles Bibliográficos
Autores principales: Awodi, U. R., Ronan, J. L., Masschelein, J., de los Santos, E. L. C., Challis, G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365063/
https://www.ncbi.nlm.nih.gov/pubmed/28451186
http://dx.doi.org/10.1039/c6sc02803a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365063/
https://www.ncbi.nlm.nih.gov/pubmed/28451186
http://dx.doi.org/10.1039/c6sc02803a

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