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Sirolimus and tacrolimus rather than cyclosporine A cause bone loss in healthy adult male rats

The aim of this work was to study the effects of cyclosporine (CsA), tacrolimus (FK-506), and rapamycin (RAPA) on bone mass, femoral microstructure, femoral biomechanical properties, and bone remodeling in healthy adult male rats. Forty-eight 5-month-old male Wistar rats were used. CsA (2 mg/kg/day)...

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Detalles Bibliográficos
Autores principales:	Rubert, Mercedes, Montero, Mercedes, Guede, David, Caeiro, Jose-Ramón, Martín-Fernández, Marta, Díaz-Curiel, Manuel, de la Piedra, Concepción
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365163/ https://www.ncbi.nlm.nih.gov/pubmed/28377957 http://dx.doi.org/10.1016/j.bonr.2015.05.003

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