Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells

OBJECTIVE: Autophagy is one of the key responses of cells to programmed cell death. Memantine, an approved anti-dementia drug, has an antiproliferative effect on cancer cells but the mechanism is poorly understood. The aim of the present study was to test the possibility of induction of autophagic c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Wan-Soo, Yeom, Mi-Young, Kang, Eun-Sun, Chung, Yong-An, Chung, Dong-Sup, Jeun, Sin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2017
Materias:
Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365296/
https://www.ncbi.nlm.nih.gov/pubmed/28264232
http://dx.doi.org/10.3340/jkns.2016.0101.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365296/
https://www.ncbi.nlm.nih.gov/pubmed/28264232
http://dx.doi.org/10.3340/jkns.2016.0101.006

Ejemplares similares