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Memantine Induces NMDAR1-Mediated Autophagic Cell Death in Malignant Glioma Cells
OBJECTIVE: Autophagy is one of the key responses of cells to programmed cell death. Memantine, an approved anti-dementia drug, has an antiproliferative effect on cancer cells but the mechanism is poorly understood. The aim of the present study was to test the possibility of induction of autophagic c...
Autores principales: | Yoon, Wan-Soo, Yeom, Mi-Young, Kang, Eun-Sun, Chung, Yong-An, Chung, Dong-Sup, Jeun, Sin-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Neurosurgical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365296/ https://www.ncbi.nlm.nih.gov/pubmed/28264232 http://dx.doi.org/10.3340/jkns.2016.0101.006 |
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