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A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading

Synthetic peptides derived from the heptad repeat (HR) of fusion (F) proteins can be used as dominant negative inhibitors to inhibit the fusion mechanism of class I viral F proteins. Here, we have performed a stapled-peptide scan across the HR2 domain of the respiratory syncytial virus (RSV) F prote...

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Detalles Bibliográficos
Autores principales: Gaillard, Vanessa, Galloux, Marie, Garcin, Dominique, Eléouët, Jean-François, Le Goffic, Ronan, Larcher, Thibaut, Rameix-Welti, Marie-Anne, Boukadiri, Abdelhak, Héritier, Julien, Segura, Jean-Manuel, Baechler, Elodie, Arrell, Miriam, Mottet-Osman, Geneviève, Nyanguile, Origène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365662/
https://www.ncbi.nlm.nih.gov/pubmed/28137809
http://dx.doi.org/10.1128/AAC.02241-16