Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis

In any drug discovery and development effort, a reduction in the time of the lead optimization cycle is critical to decrease the time to license and reduce costs. In addition, ethical guidelines call for the more ethical use of animals to minimize the number of animals used and decrease their suffer...

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Detalles Bibliográficos
Autores principales: Caridha, Diana, Parriot, Sandi, Hudson, Thomas H., Lang, Thierry, Ngundam, Franklyn, Leed, Susan, Sena, Jenell, Harris, Michael, O'Neil, Michael, Sciotti, Richard, Read, Lisa, Lecoeur, Herve, Hickman, Mark, Grogl, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365718/
https://www.ncbi.nlm.nih.gov/pubmed/28137819
http://dx.doi.org/10.1128/AAC.02048-16

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