Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer

BACKGROUND: Psychological stress increases the circulating levels of the stress hormones cortisol and norepinephrine (NE). Chronic exposure to elevated stress hormones has been linked to a reduced response to chemotherapy through induction of DNA damage. We hypothesize that stress hormone signalling...

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Detalles Bibliográficos
Autores principales: Flaherty, Renée L., Owen, Matthew, Fagan-Murphy, Aidan, Intabli, Haya, Healy, David, Patel, Anika, Allen, Marcus C., Patel, Bhavik A., Flint, Melanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366114/
https://www.ncbi.nlm.nih.gov/pubmed/28340615
http://dx.doi.org/10.1186/s13058-017-0823-8

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