Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension

BACKGROUND: Right ventricular structure and function is a major predictor of outcomes in pulmonary hypertension (PH), yet the underlying mechanisms remain poorly understood. Growing evidence suggests the importance of autophagy in cardiac remodeling; however, its dynamics in the process of right ven...

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Detalles Bibliográficos
Autores principales: Deng, Yan, Wu, Weifeng, Guo, Shenglan, Chen, Yuming, Liu, Chang, Gao, Xingcui, Wei, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366117/
https://www.ncbi.nlm.nih.gov/pubmed/28340591
http://dx.doi.org/10.1186/s12931-017-0536-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366117/
https://www.ncbi.nlm.nih.gov/pubmed/28340591
http://dx.doi.org/10.1186/s12931-017-0536-7

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