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Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension

BACKGROUND: Right ventricular structure and function is a major predictor of outcomes in pulmonary hypertension (PH), yet the underlying mechanisms remain poorly understood. Growing evidence suggests the importance of autophagy in cardiac remodeling; however, its dynamics in the process of right ven...

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Detalles Bibliográficos
Autores principales:	Deng, Yan, Wu, Weifeng, Guo, Shenglan, Chen, Yuming, Liu, Chang, Gao, Xingcui, Wei, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366117/ https://www.ncbi.nlm.nih.gov/pubmed/28340591 http://dx.doi.org/10.1186/s12931-017-0536-7

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