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Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1(-/-) mouse model

BACKGROUND: Severe hyperbilirubinemia is toxic during central nervous system development. Prolonged and uncontrolled high levels of unconjugated bilirubin lead to bilirubin-induced neurological damage and eventually death by kernicterus. Bilirubin neurotoxicity is characterized by a wide array of ne...

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Detalles Bibliográficos
Autores principales:	Vodret, Simone, Bortolussi, Giulia, Jašprová, Jana, Vitek, Libor, Muro, Andrés F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366125/ https://www.ncbi.nlm.nih.gov/pubmed/28340583 http://dx.doi.org/10.1186/s12974-017-0838-1

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