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MeDeCom: discovery and quantification of latent components of heterogeneous methylomes
It is important for large-scale epigenomic studies to determine and explore the nature of hidden confounding variation, most importantly cell composition. We developed MeDeCom as a novel reference-free computational framework that allows the decomposition of complex DNA methylomes into latent methyl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366155/ https://www.ncbi.nlm.nih.gov/pubmed/28340624 http://dx.doi.org/10.1186/s13059-017-1182-6 |