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Characterization of the specific interaction between the DNA aptamer sgc8c and protein tyrosine kinase-7 receptors at the surface of T-cells by biosensing AFM
We studied the interaction of the specific DNA aptamer sgc8c immobilized at the AFM tip with its corresponding receptor, the protein tyrosine kinase-7 (PTK7) embedded in the membrane of acute lymphoblastic leukemia (ALL) cells (Jurkat T-cells). Performing single molecule force spectroscopy (SMFS) ex...
Autores principales: | Leitner, Michael, Poturnayova, Alexandra, Lamprecht, Constanze, Weich, Sabine, Snejdarkova, Maja, Karpisova, Ivana, Hianik, Tibor, Ebner, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366180/ https://www.ncbi.nlm.nih.gov/pubmed/28229174 http://dx.doi.org/10.1007/s00216-017-0238-5 |
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