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Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa

Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD)...

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Autores principales: Afolabi, Kayode O., Iweriebor, Benson C., Okoh, Anthony I., Obi, Larry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366187/
https://www.ncbi.nlm.nih.gov/pubmed/28386278
http://dx.doi.org/10.1155/2017/6807964
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author Afolabi, Kayode O.
Iweriebor, Benson C.
Okoh, Anthony I.
Obi, Larry C.
author_facet Afolabi, Kayode O.
Iweriebor, Benson C.
Okoh, Anthony I.
Obi, Larry C.
author_sort Afolabi, Kayode O.
collection PubMed
description Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD) in Europe. PCV2 infections, specifically PMWS, had impacted huge economic loss on swine production at different regions of the world. It has been studied and reported at different parts of the globe including: North and South America, Europe, Asia, Oceania, Middle East, and the Caribbean. However, till date, this virus and its associated diseases have been grossly understudied in sub-Sahara African region and the entire continent at large. Two out of forty-nine, representing just about 4% of countries that make up sub-Sahara Africa presently, have limited records on reported cases and occurrence of the viral pathogen despite the ubiquitous nature of the virus. This review presents an overview of the discovery of Porcine circovirus and its associated diseases in global pig herds and emphasizes the latest trends in PCV2 vaccines and antiviral drugs development and the information gaps that exist on the occurrence of this important viral pathogen in swine herds of sub-Saharan Africa countries. This will serve as wake-up call for immediate and relevant actions by stakeholders in the region.
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spelling pubmed-53661872017-04-06 Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa Afolabi, Kayode O. Iweriebor, Benson C. Okoh, Anthony I. Obi, Larry C. Adv Virol Review Article Globally, Porcine circovirus type 2 (PCV2) is a recognized viral pathogen of great economic value in pig farming. It is the major cause of ravaging postweaning multisystemic wasting syndrome (PMWS) and many other disease syndromes generally regarded as Porcine circovirus associated diseases (PCVAD) in Europe. PCV2 infections, specifically PMWS, had impacted huge economic loss on swine production at different regions of the world. It has been studied and reported at different parts of the globe including: North and South America, Europe, Asia, Oceania, Middle East, and the Caribbean. However, till date, this virus and its associated diseases have been grossly understudied in sub-Sahara African region and the entire continent at large. Two out of forty-nine, representing just about 4% of countries that make up sub-Sahara Africa presently, have limited records on reported cases and occurrence of the viral pathogen despite the ubiquitous nature of the virus. This review presents an overview of the discovery of Porcine circovirus and its associated diseases in global pig herds and emphasizes the latest trends in PCV2 vaccines and antiviral drugs development and the information gaps that exist on the occurrence of this important viral pathogen in swine herds of sub-Saharan Africa countries. This will serve as wake-up call for immediate and relevant actions by stakeholders in the region. Hindawi 2017 2017-03-12 /pmc/articles/PMC5366187/ /pubmed/28386278 http://dx.doi.org/10.1155/2017/6807964 Text en Copyright © 2017 Kayode O. Afolabi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Afolabi, Kayode O.
Iweriebor, Benson C.
Okoh, Anthony I.
Obi, Larry C.
Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title_full Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title_fullStr Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title_full_unstemmed Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title_short Global Status of Porcine circovirus Type 2 and Its Associated Diseases in Sub-Saharan Africa
title_sort global status of porcine circovirus type 2 and its associated diseases in sub-saharan africa
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366187/
https://www.ncbi.nlm.nih.gov/pubmed/28386278
http://dx.doi.org/10.1155/2017/6807964
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