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Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges

Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its...

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Autores principales: Pritsini, Filippa, Kanakis, Georgios A., Kyrgios, Ioannis, Kotanidou, Eleni P., Litou, Eleni, Mouzaki, Konstantina, Kleisarchaki, Aggeliki, Goulis, Dimitrios G., Galli-Tsinopoulou, Assimina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366217/
https://www.ncbi.nlm.nih.gov/pubmed/28386489
http://dx.doi.org/10.1155/2017/8313162
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author Pritsini, Filippa
Kanakis, Georgios A.
Kyrgios, Ioannis
Kotanidou, Eleni P.
Litou, Eleni
Mouzaki, Konstantina
Kleisarchaki, Aggeliki
Goulis, Dimitrios G.
Galli-Tsinopoulou, Assimina
author_facet Pritsini, Filippa
Kanakis, Georgios A.
Kyrgios, Ioannis
Kotanidou, Eleni P.
Litou, Eleni
Mouzaki, Konstantina
Kleisarchaki, Aggeliki
Goulis, Dimitrios G.
Galli-Tsinopoulou, Assimina
author_sort Pritsini, Filippa
collection PubMed
description Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its variable phenotype, AIS is not diagnosed at the proper age that would allow optimal psychological and medical support to the patient. Therapeutic approaches are not established, mainly due to the rarity of the disease. In addition, various social and ethical consequences may emerge. The aim of this double case report is to outline the difficulties that may rise during diagnostic, therapeutic, and psychological approach of AIS, especially concerning the handling of the relatives' reaction.
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spelling pubmed-53662172017-04-06 Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges Pritsini, Filippa Kanakis, Georgios A. Kyrgios, Ioannis Kotanidou, Eleni P. Litou, Eleni Mouzaki, Konstantina Kleisarchaki, Aggeliki Goulis, Dimitrios G. Galli-Tsinopoulou, Assimina Case Rep Endocrinol Case Report Androgen Insensitivity Syndrome (AIS) and its heterogeneous phenotypes comprise the pieces of a challenging clinical problem. The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. Due to its variable phenotype, AIS is not diagnosed at the proper age that would allow optimal psychological and medical support to the patient. Therapeutic approaches are not established, mainly due to the rarity of the disease. In addition, various social and ethical consequences may emerge. The aim of this double case report is to outline the difficulties that may rise during diagnostic, therapeutic, and psychological approach of AIS, especially concerning the handling of the relatives' reaction. Hindawi 2017 2017-03-12 /pmc/articles/PMC5366217/ /pubmed/28386489 http://dx.doi.org/10.1155/2017/8313162 Text en Copyright © 2017 Filippa Pritsini et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pritsini, Filippa
Kanakis, Georgios A.
Kyrgios, Ioannis
Kotanidou, Eleni P.
Litou, Eleni
Mouzaki, Konstantina
Kleisarchaki, Aggeliki
Goulis, Dimitrios G.
Galli-Tsinopoulou, Assimina
Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_full Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_fullStr Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_full_unstemmed Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_short Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges
title_sort psychological aspects of androgen insensitivity syndrome: two cases illustrating therapeutical challenges
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366217/
https://www.ncbi.nlm.nih.gov/pubmed/28386489
http://dx.doi.org/10.1155/2017/8313162
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