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Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry

Highlight: Participants were non-clinical young adults with different restrained eating levels. We assessed relations of restrained eating (RE) with regional gray matter volume (rGMV). High RE scores were related to larger GMV in specific areas related to reward. High RE scores were also linked to l...

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Autores principales: Su, Yanhua, Jackson, Todd, Wei, Dongtao, Qiu, Jiang, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366353/
https://www.ncbi.nlm.nih.gov/pubmed/28396646
http://dx.doi.org/10.3389/fpsyg.2017.00443
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author Su, Yanhua
Jackson, Todd
Wei, Dongtao
Qiu, Jiang
Chen, Hong
author_facet Su, Yanhua
Jackson, Todd
Wei, Dongtao
Qiu, Jiang
Chen, Hong
author_sort Su, Yanhua
collection PubMed
description Highlight: Participants were non-clinical young adults with different restrained eating levels. We assessed relations of restrained eating (RE) with regional gray matter volume (rGMV). High RE scores were related to larger GMV in specific areas related to reward. High RE scores were also linked to less GMV in regions related to response inhibition. Objective: Dieting is a popular method of weight control. However, few dieters are able to maintain initial weight losses over an extended period of time. Why do most restrained dieters fail to lose weight? Alterations in brain structures associated with restrained eating (RE) represent one potentially important mechanism that contributes to difficulties in maintaining weight loss within this group. To evaluate this contention, we investigated associations between intentional, sustained restriction of food intake to lose or maintain body weight, and regional gray matter volume (rGMV) within a large non-clinical young adult, sample. Methods: Participants (150 women, 108 men) completed measures of RE and demographics prior to undergoing an MRI scan. Voxel-based morphometry (VBM) evaluated strengths of association between RE scores and rGMV. Results: Higher RE levels corresponded to more rGMV in regions linked to risk of overeating and binge-eating including the left insula and orbitofrontal cortex (OFC). Conversely, RE had significant negative correlations with rGMV in the left and right posterior cingulum gyrus, regions linked to inhibitory control and potential risk for future weight gain. Conclusions: Together, findings suggested individual differences in RE among young adults correspond to GMV variability in regions linked to overweight and obesity risk.
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spelling pubmed-53663532017-04-10 Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry Su, Yanhua Jackson, Todd Wei, Dongtao Qiu, Jiang Chen, Hong Front Psychol Psychology Highlight: Participants were non-clinical young adults with different restrained eating levels. We assessed relations of restrained eating (RE) with regional gray matter volume (rGMV). High RE scores were related to larger GMV in specific areas related to reward. High RE scores were also linked to less GMV in regions related to response inhibition. Objective: Dieting is a popular method of weight control. However, few dieters are able to maintain initial weight losses over an extended period of time. Why do most restrained dieters fail to lose weight? Alterations in brain structures associated with restrained eating (RE) represent one potentially important mechanism that contributes to difficulties in maintaining weight loss within this group. To evaluate this contention, we investigated associations between intentional, sustained restriction of food intake to lose or maintain body weight, and regional gray matter volume (rGMV) within a large non-clinical young adult, sample. Methods: Participants (150 women, 108 men) completed measures of RE and demographics prior to undergoing an MRI scan. Voxel-based morphometry (VBM) evaluated strengths of association between RE scores and rGMV. Results: Higher RE levels corresponded to more rGMV in regions linked to risk of overeating and binge-eating including the left insula and orbitofrontal cortex (OFC). Conversely, RE had significant negative correlations with rGMV in the left and right posterior cingulum gyrus, regions linked to inhibitory control and potential risk for future weight gain. Conclusions: Together, findings suggested individual differences in RE among young adults correspond to GMV variability in regions linked to overweight and obesity risk. Frontiers Media S.A. 2017-03-27 /pmc/articles/PMC5366353/ /pubmed/28396646 http://dx.doi.org/10.3389/fpsyg.2017.00443 Text en Copyright © 2017 Su, Jackson, Wei, Qiu and Chen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Su, Yanhua
Jackson, Todd
Wei, Dongtao
Qiu, Jiang
Chen, Hong
Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title_full Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title_fullStr Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title_full_unstemmed Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title_short Regional Gray Matter Volume Is Associated with Restrained Eating in Healthy Chinese Young Adults: Evidence from Voxel-Based Morphometry
title_sort regional gray matter volume is associated with restrained eating in healthy chinese young adults: evidence from voxel-based morphometry
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366353/
https://www.ncbi.nlm.nih.gov/pubmed/28396646
http://dx.doi.org/10.3389/fpsyg.2017.00443
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