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Protective Effect of Edaravone Against Cyclosporine-Induced Chronic Nephropathy Through Antioxidant and Nitric Oxide Modulating Pathways in Rats

BACKGROUND: Cyclosporine A (CsA) is an immunosuppressant with therapeutic indications in various immunological diseases; however, its use is associated with chronic nephropathy. Oxidative stress has a crucial role in CsA-induced nephrotoxicity. The present study evaluates the protective effect of ed...

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Detalles Bibliográficos
Autores principales: Sattarinezhad, Elahe, Panjehshahin, Mohammad Reza, Torabinezhad, Simin, Kamali-Sarvestani, Eskandar, Farjadian, Shirin, Pirsalami, Fatema, Moezi, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366365/
https://www.ncbi.nlm.nih.gov/pubmed/28360443