Cargando…
Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese
Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies. Botulism is an essential health problem because of its high mortality. The diagnosis of botulism, especially in spora...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Journal of Medical Sciences
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366369/ https://www.ncbi.nlm.nih.gov/pubmed/28360447 |
_version_ | 1782517579028365312 |
---|---|
author | Rafie, Shahram Salmanzadeh, Shokrollah Mehramiri, Asieh Nejati, Adel |
author_facet | Rafie, Shahram Salmanzadeh, Shokrollah Mehramiri, Asieh Nejati, Adel |
author_sort | Rafie, Shahram |
collection | PubMed |
description | Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies. Botulism is an essential health problem because of its high mortality. The diagnosis of botulism, especially in sporadic cases, is a medical challenge and a high clinical suspicion is necessary for early recognition. So, every physician should be familiar with its signs and symptoms for early detection and treatment. We describe a family with dysphasia and acute paralysis after the ingestion of locally made cheese. The clinical presentations of the 1st patient were similar to myasthenic crisis and she, therefore, received plasma exchange. After the appearance of similar symptoms in the other family members, they were treated with polyvalent botulinum antitoxin and diagnosis was confirmed by toxicology and detection of serotype A botulinum toxin in cheese and stool samples. Uncommon clinical presentations and unusual sources of botulinum toxin should be kept in mind because of the importance of early diagnosis and treatment. |
format | Online Article Text |
id | pubmed-5366369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Iranian Journal of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-53663692017-03-30 Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese Rafie, Shahram Salmanzadeh, Shokrollah Mehramiri, Asieh Nejati, Adel Iran J Med Sci Case Report Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies. Botulism is an essential health problem because of its high mortality. The diagnosis of botulism, especially in sporadic cases, is a medical challenge and a high clinical suspicion is necessary for early recognition. So, every physician should be familiar with its signs and symptoms for early detection and treatment. We describe a family with dysphasia and acute paralysis after the ingestion of locally made cheese. The clinical presentations of the 1st patient were similar to myasthenic crisis and she, therefore, received plasma exchange. After the appearance of similar symptoms in the other family members, they were treated with polyvalent botulinum antitoxin and diagnosis was confirmed by toxicology and detection of serotype A botulinum toxin in cheese and stool samples. Uncommon clinical presentations and unusual sources of botulinum toxin should be kept in mind because of the importance of early diagnosis and treatment. Iranian Journal of Medical Sciences 2017-03 /pmc/articles/PMC5366369/ /pubmed/28360447 Text en Copyright: © Iranian Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Rafie, Shahram Salmanzadeh, Shokrollah Mehramiri, Asieh Nejati, Adel Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title | Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title_full | Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title_fullStr | Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title_full_unstemmed | Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title_short | Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese |
title_sort | botulism outbreak in a family after ingestion of locally produced cheese |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366369/ https://www.ncbi.nlm.nih.gov/pubmed/28360447 |
work_keys_str_mv | AT rafieshahram botulismoutbreakinafamilyafteringestionoflocallyproducedcheese AT salmanzadehshokrollah botulismoutbreakinafamilyafteringestionoflocallyproducedcheese AT mehramiriasieh botulismoutbreakinafamilyafteringestionoflocallyproducedcheese AT nejatiadel botulismoutbreakinafamilyafteringestionoflocallyproducedcheese |