The Child as a Surrogate for Diagnosis of Lupus in the Mother

Introduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gesta...

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Autores principales: Adelowo, Olufemi O., Ohagwu, Kenneth A., Aigbokhan, Ejiehi E., Akintayo, Richard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366761/
https://www.ncbi.nlm.nih.gov/pubmed/28386505
http://dx.doi.org/10.1155/2017/8247591
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author Adelowo, Olufemi O.
Ohagwu, Kenneth A.
Aigbokhan, Ejiehi E.
Akintayo, Richard O.
author_facet Adelowo, Olufemi O.
Ohagwu, Kenneth A.
Aigbokhan, Ejiehi E.
Akintayo, Richard O.
author_sort Adelowo, Olufemi O.
collection PubMed
description Introduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gestation following detection of fetal bradycardia during routine antenatal clinic visit. Results. The mother was seropositive for antinuclear antibody (ANA) and anti-Ro/SSA and had elevated erythrocyte sedimentation rate. The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA. Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block.
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spelling pubmed-53667612017-04-06 The Child as a Surrogate for Diagnosis of Lupus in the Mother Adelowo, Olufemi O. Ohagwu, Kenneth A. Aigbokhan, Ejiehi E. Akintayo, Richard O. Case Rep Rheumatol Case Report Introduction. Neonatal lupus erythematosus (NLE) is an acquired disease of the newborn caused by transplacental transfer of maternal anti-Ro/SSA, anti-La/SSB, and infrequently anti-U1 RNP antibodies. Methodology. This is a case report of a male infant delivered via Caesarean section at 36-week gestation following detection of fetal bradycardia during routine antenatal clinic visit. Results. The mother was seropositive for antinuclear antibody (ANA) and anti-Ro/SSA and had elevated erythrocyte sedimentation rate. The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA. Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block. Hindawi 2017 2017-03-13 /pmc/articles/PMC5366761/ /pubmed/28386505 http://dx.doi.org/10.1155/2017/8247591 Text en Copyright © 2017 Olufemi O. Adelowo et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Adelowo, Olufemi O.
Ohagwu, Kenneth A.
Aigbokhan, Ejiehi E.
Akintayo, Richard O.
The Child as a Surrogate for Diagnosis of Lupus in the Mother
title The Child as a Surrogate for Diagnosis of Lupus in the Mother
title_full The Child as a Surrogate for Diagnosis of Lupus in the Mother
title_fullStr The Child as a Surrogate for Diagnosis of Lupus in the Mother
title_full_unstemmed The Child as a Surrogate for Diagnosis of Lupus in the Mother
title_short The Child as a Surrogate for Diagnosis of Lupus in the Mother
title_sort child as a surrogate for diagnosis of lupus in the mother
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366761/
https://www.ncbi.nlm.nih.gov/pubmed/28386505
http://dx.doi.org/10.1155/2017/8247591
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