Cargando…
Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination
Dissecting the cellular signaling that governs the motility of eukaryotic cells is one of the fundamental tasks of modern cell biology, not only because of the large number of physiological processes in which cell migration is crucial, but even more so because of the pathological ones, in particular...
Autores principales: | Di Blasio, Laura, Gagliardi, Paolo A., Puliafito, Alberto, Primo, Luca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366820/ https://www.ncbi.nlm.nih.gov/pubmed/28287465 http://dx.doi.org/10.3390/cancers9030025 |
Ejemplares similares
-
Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1)
por: King, Charles C., et al.
Publicado: (2015) -
PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction
por: Gagliardi, Paolo Armando, et al.
Publicado: (2014) -
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
por: Levina, Aleksandra, et al.
Publicado: (2022) -
Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
por: Wood, C. David, et al.
Publicado: (2007) -
Essential role of PDK1 in regulating endothelial cell migration
por: Primo, Luca, et al.
Publicado: (2007)