Differential roles of caspase-1 and caspase-11 in infection and inflammation

Caspase-1, also known as interleukin-1β (IL-1β)-converting enzyme (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane biogenesis. On activation within an inflammasome complex, caspase-1 induces pyroptosis and converts pro-IL-1β and pro-IL-18 into their...

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Detalles Bibliográficos
Autores principales: Ming Man, Si, Karki, Rajendra, Briard, Benoit, Burton, Amanda, Gingras, Sebastien, Pelletier, Stephane, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366862/
https://www.ncbi.nlm.nih.gov/pubmed/28345580
http://dx.doi.org/10.1038/srep45126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366862/
https://www.ncbi.nlm.nih.gov/pubmed/28345580
http://dx.doi.org/10.1038/srep45126

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