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WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel
WT1 is a transcription factor which regulates the epithelial-mesenchymal balance during embryonic development and, if mutated, can lead to the formation of Wilms’ tumour, the most common paediatric kidney cancer. Its expression has also been reported in several adult tumour types, including breast c...
Autores principales: | Artibani, Mara, Sims, Andrew H., Slight, Joan, Aitken, Stuart, Thornburn, Anna, Muir, Morwenna, Brunton, Valerie G., Del-Pozo, Jorge, Morrison, Linda R., Katz, Elad, Hastie, Nicholas D., Hohenstein, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366898/ https://www.ncbi.nlm.nih.gov/pubmed/28345629 http://dx.doi.org/10.1038/srep45255 |
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