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A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions
Integration of the intestinal epithelium and the mucosal immune system is critical for gut homeostasis. The intestinal epithelium is a functional barrier that secludes luminal content, senses changes in the gut microenvironment, and releases immune regulators that signal underlying immune cells. How...
Autores principales: | Noel, Gaelle, Baetz, Nicholas W., Staab, Janet F., Donowitz, Mark, Kovbasnjuk, Olga, Pasetti, Marcela F., Zachos, Nicholas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366908/ https://www.ncbi.nlm.nih.gov/pubmed/28345602 http://dx.doi.org/10.1038/srep45270 |
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