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Total Synthesis and Stereochemical Assignment of Nostosin B

Nostosins A and B were isolated from a hydrophilic extract of Nostoc sp. strain from Iran, which exhibits excellent trypsin inhibitory activity. Nostosin A was the most potent natural tripeptide aldehyde as trypsin inhibitor up to now. Both r- and s-2-hydroxy-4-(4-hydroxy-phenyl)butanoic acid (Hhpba...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoji, Feng, Junmin, Xu, Zhengshuang, Ye, Tao, Meng, Yi, Zhang, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367015/
https://www.ncbi.nlm.nih.gov/pubmed/28264450
http://dx.doi.org/10.3390/md15030058