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Phakellistatins: An Underwater Unsolved Puzzle
A critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1–19), cytotoxic proline-rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various-sized natural macrocycles are described, alo...
Autores principales: | Meli, Alessandra, Tedesco, Consiglia, Della Sala, Giorgio, Schettini, Rosaria, Albericio, Fernando, De Riccardis, Francesco, Izzo, Irene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367035/ https://www.ncbi.nlm.nih.gov/pubmed/28335479 http://dx.doi.org/10.3390/md15030078 |
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