Cargando…
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of inherited and somatic variants of all types. CIViC is committed to open-source code, open-access content, public applicatio...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367263/ https://www.ncbi.nlm.nih.gov/pubmed/28138153 http://dx.doi.org/10.1038/ng.3774 |
| _version_ | 1782517740073910272 |
|---|---|
| author | Griffith, Malachi Spies, Nicholas C Krysiak, Kilannin McMichael, Joshua F Coffman, Adam C Danos, Arpad M Ainscough, Benjamin J Ramirez, Cody A Rieke, Damian T Kujan, Lynzey Barnell, Erica K Wagner, Alex H Skidmore, Zachary L Wollam, Amber Liu, Connor J Jones, Martin R Bilski, Rachel L Lesurf, Robert Feng, Yan-Yang Shah, Nakul M Bonakdar, Melika Trani, Lee Matlock, Matthew Ramu, Avinash Campbell, Katie M Spies, Gregory C Graubert, Aaron P Gangavarapu, Karthik Eldred, James M Larson, David E Walker, Jason R Good, Benjamin M Wu, Chunlei Su, Andrew I Dienstmann, Rodrigo Margolin, Adam A Tamborero, David Lopez-Bigas, Nuria Jones, Steven J M Bose, Ron Spencer, David H Wartman, Lukas D Wilson, Richard K Mardis, Elaine R Griffith, Obi L |
| author_facet | Griffith, Malachi Spies, Nicholas C Krysiak, Kilannin McMichael, Joshua F Coffman, Adam C Danos, Arpad M Ainscough, Benjamin J Ramirez, Cody A Rieke, Damian T Kujan, Lynzey Barnell, Erica K Wagner, Alex H Skidmore, Zachary L Wollam, Amber Liu, Connor J Jones, Martin R Bilski, Rachel L Lesurf, Robert Feng, Yan-Yang Shah, Nakul M Bonakdar, Melika Trani, Lee Matlock, Matthew Ramu, Avinash Campbell, Katie M Spies, Gregory C Graubert, Aaron P Gangavarapu, Karthik Eldred, James M Larson, David E Walker, Jason R Good, Benjamin M Wu, Chunlei Su, Andrew I Dienstmann, Rodrigo Margolin, Adam A Tamborero, David Lopez-Bigas, Nuria Jones, Steven J M Bose, Ron Spencer, David H Wartman, Lukas D Wilson, Richard K Mardis, Elaine R Griffith, Obi L |
| author_sort | Griffith, Malachi |
| collection | PubMed |
| description | CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of inherited and somatic variants of all types. CIViC is committed to open-source code, open-access content, public application programming interfaces (APIs) and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine. |
| format | Online Article Text |
| id | pubmed-5367263 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-53672632017-03-27 CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer Griffith, Malachi Spies, Nicholas C Krysiak, Kilannin McMichael, Joshua F Coffman, Adam C Danos, Arpad M Ainscough, Benjamin J Ramirez, Cody A Rieke, Damian T Kujan, Lynzey Barnell, Erica K Wagner, Alex H Skidmore, Zachary L Wollam, Amber Liu, Connor J Jones, Martin R Bilski, Rachel L Lesurf, Robert Feng, Yan-Yang Shah, Nakul M Bonakdar, Melika Trani, Lee Matlock, Matthew Ramu, Avinash Campbell, Katie M Spies, Gregory C Graubert, Aaron P Gangavarapu, Karthik Eldred, James M Larson, David E Walker, Jason R Good, Benjamin M Wu, Chunlei Su, Andrew I Dienstmann, Rodrigo Margolin, Adam A Tamborero, David Lopez-Bigas, Nuria Jones, Steven J M Bose, Ron Spencer, David H Wartman, Lukas D Wilson, Richard K Mardis, Elaine R Griffith, Obi L Nat Genet Article CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of inherited and somatic variants of all types. CIViC is committed to open-source code, open-access content, public application programming interfaces (APIs) and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine. 2017-01-31 /pmc/articles/PMC5367263/ /pubmed/28138153 http://dx.doi.org/10.1038/ng.3774 Text en http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) licence. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons licence, users will need to obtain permission from the licence holder to reproduce the material. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ |
| spellingShingle | Article Griffith, Malachi Spies, Nicholas C Krysiak, Kilannin McMichael, Joshua F Coffman, Adam C Danos, Arpad M Ainscough, Benjamin J Ramirez, Cody A Rieke, Damian T Kujan, Lynzey Barnell, Erica K Wagner, Alex H Skidmore, Zachary L Wollam, Amber Liu, Connor J Jones, Martin R Bilski, Rachel L Lesurf, Robert Feng, Yan-Yang Shah, Nakul M Bonakdar, Melika Trani, Lee Matlock, Matthew Ramu, Avinash Campbell, Katie M Spies, Gregory C Graubert, Aaron P Gangavarapu, Karthik Eldred, James M Larson, David E Walker, Jason R Good, Benjamin M Wu, Chunlei Su, Andrew I Dienstmann, Rodrigo Margolin, Adam A Tamborero, David Lopez-Bigas, Nuria Jones, Steven J M Bose, Ron Spencer, David H Wartman, Lukas D Wilson, Richard K Mardis, Elaine R Griffith, Obi L CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title | CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title_full | CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title_fullStr | CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title_full_unstemmed | CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title_short | CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| title_sort | civic is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367263/ https://www.ncbi.nlm.nih.gov/pubmed/28138153 http://dx.doi.org/10.1038/ng.3774 |
| work_keys_str_mv | AT griffithmalachi civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT spiesnicholasc civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT krysiakkilannin civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT mcmichaeljoshuaf civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT coffmanadamc civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT danosarpadm civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT ainscoughbenjaminj civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT ramirezcodya civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT riekedamiant civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT kujanlynzey civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT barnellericak civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT wagneralexh civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT skidmorezacharyl civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT wollamamber civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT liuconnorj civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT jonesmartinr civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT bilskirachell civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT lesurfrobert civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT fengyanyang civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT shahnakulm civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT bonakdarmelika civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT tranilee civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT matlockmatthew civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT ramuavinash civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT campbellkatiem civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT spiesgregoryc civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT graubertaaronp civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT gangavarapukarthik civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT eldredjamesm civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT larsondavide civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT walkerjasonr civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT goodbenjaminm civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT wuchunlei civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT suandrewi civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT dienstmannrodrigo civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT margolinadama civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT tamborerodavid civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT lopezbigasnuria civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT jonesstevenjm civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT boseron civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT spencerdavidh civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT wartmanlukasd civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT wilsonrichardk civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT mardiselainer civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer AT griffithobil civicisacommunityknowledgebaseforexpertcrowdsourcingtheclinicalinterpretationofvariantsincancer |