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Increased expression of PD-L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

Cytotoxic T lymphocyte dysfunction is frequently associated with PD-L1/PD-1 pathway activation, and is a principal obstacle in cancer therapy. In the present study, the mechanisms underlying the human papillomavirus (HPV)-induced evasion of cervical cancer cells to the host immune system via the pro...

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Detalles Bibliográficos
Autores principales: Liu, Chaoqi, Lu, Jiao, Tian, Huiqun, Du, Wei, Zhao, Lin, Feng, Jing, Yuan, Ding, Li, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367331/
https://www.ncbi.nlm.nih.gov/pubmed/28075442
http://dx.doi.org/10.3892/mmr.2017.6102