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FIGNL1 is overexpressed in small cell lung cancer patients and enhances NCI-H446 cell resistance to cisplatin and etoposide

Abnormal DNA repair plays an important role in tumor occurrence, progression and resistance to therapy. Fidgetin-like 1 (FIGNL1) expression was assayed in 42 small cell lung cancer (SCLC) and 45 normal lung specimens from Chinese patients by qRT-PCR. Notably, FIGNL1 was upregulated by 1.5-fold in th...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Li, Jianlei, Yao, Xiaoling, Lin, Shuangjun, Gu, Ye, Xu, Jianfang, Deng, Zixin, Ma, Wei, Zhang, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367342/
https://www.ncbi.nlm.nih.gov/pubmed/28260065
http://dx.doi.org/10.3892/or.2017.5483

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