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Computational Design of Self-Assembling Cyclic Protein Homo-oligomers

Self-assembling cyclic protein homo-oligomers play important roles in biology and the ability to generate custom homo-oligomeric structures could enable new approaches to probe biological function. Here we report a general approach to design cyclic homo-oligomers that employs a new residue pair tran...

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Detalles Bibliográficos
Autores principales: Fallas, Jorge A., Ueda, George, Sheffler, William, Nguyen, Vanessa, McNamara, Dan E., Sankaran, Banumathi, Pereira, Jose Henrique, Parmeggiani, Fabio, Brunette, TJ, Cascio, Duilio, Yeates, Todd R., Zwart, Peter, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367466/
https://www.ncbi.nlm.nih.gov/pubmed/28338692
http://dx.doi.org/10.1038/nchem.2673

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