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The Analgesic Effects of (5R,6R)6-(3-Propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1] Octane on a Mouse Model of Neuropathic Pain

BACKGROUND: Both pharmacologic and genetic approaches have been used to study the involvement of the muscarinic acetylcholine system in the regulation of chronic pain. Previous studies suggest that the M2 and M4 subtypes of muscarinic acetylcholine receptors (mAChRs) are important targets for the de...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Jie, Zuo, Zhen-Xing, Zhang, Mei, Feng, Zhi-Hui, Yan, Min, Li, Xiang-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367490/
https://www.ncbi.nlm.nih.gov/pubmed/28002166
http://dx.doi.org/10.1213/ANE.0000000000001755