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Downregulation of miR-139-5p contributes to the antiapoptotic effect of liraglutide on the diabetic rat pancreas and INS-1 cells by targeting IRS1

Liraglutide is administered as glucagon-like peptide-1 (GLP-1) receptor agonist for diabetic patients and can protect pancreatic β-cells by inhibiting their apoptosis. MicroRNA-139-5p (miRNA-139-5p) participates in the regulation of cancer cell apoptosis. However, it is not clear whether miR-139-5p...

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Detalles Bibliográficos
Autores principales:	Li, Jin, Su, Lei, Gong, Ying-ying, Ding, Mei-lin, Hong, Shu-bin, Yu, Shuang, Xiao, Hai-peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367678/ https://www.ncbi.nlm.nih.gov/pubmed/28346520 http://dx.doi.org/10.1371/journal.pone.0173576

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