Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

At a time when the antibiotic drug discovery pipeline has stalled, antibiotic resistance is accelerating with catastrophic implications for our ability to treat bacterial infections. Globally we face the prospect of a future when common infections can once again kill. Anti-virulence approaches that...

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Detalles Bibliográficos
Autores principales: Mohanty, Biswaranjan, Rimmer, Kieran, McMahon, Róisín M., Headey, Stephen J., Vazirani, Mansha, Shouldice, Stephen R., Coinçon, Mathieu, Tay, Stephanie, Morton, Craig J., Simpson, Jamie S., Martin, Jennifer L., Scanlon, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367682/
https://www.ncbi.nlm.nih.gov/pubmed/28346540
http://dx.doi.org/10.1371/journal.pone.0173436

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