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Tocilizumab (Anti-IL-6R) Suppressed TNFα Production by Human Monocytes in an In Vitro Model of Anti-HLA Antibody-Induced Antibody-Dependent Cellular Cytotoxicity

BACKGROUND: We previously demonstrated that natural killer (NK) cells activated via FcγRIIIa (CD16) interactions with anti-HLA antibodies binding to peripheral blood mononuclear cells (PBMCs) in the in vitro antibody-dependent cellular cytotoxicity (ADCC) assay produced IFNγ. Here we investigate if...

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Detalles Bibliográficos
Autores principales:	Shin, Bong-Ha, Ge, Shili, Mirocha, James, Jordan, Stanley C., Toyoda, Mieko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Basic Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367756/ https://www.ncbi.nlm.nih.gov/pubmed/28361123 http://dx.doi.org/10.1097/TXD.0000000000000653

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