Cargando…

Effect of miR-146 targeted HDMCP up-regulation in the pathogenesis of nonalcoholic steatohepatitis

BACKGROUNDS/AIMS: Mitochondrial dysfunction plays an important role inthe pathogenesis of nonalcoholic steatohepatitis (NASH), where uncoupling protein (UCP) is actively involved. We previously reported the uncoupling activity of HDMCP and its role in liver steatosis. We now aim to investigate the d...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Xi, Liu, Jiang, Chen, Yi-peng, Xiang, Zun, Ding, Jie-xia, Li, You-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367781/
https://www.ncbi.nlm.nih.gov/pubmed/28346483
http://dx.doi.org/10.1371/journal.pone.0174218