Patient-specific modeling of individual sickle cell behavior under transient hypoxia

Sickle cell disease (SCD) is a highly complex genetic blood disorder in which red blood cells (RBC) exhibit heterogeneous morphology changes and decreased deformability. We employ a kinetic model for cell morphological sickling that invokes parameters derived from patient-specific data. This model i...

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Detalles Bibliográficos
Autores principales: Li, Xuejin, Du, E., Dao, Ming, Suresh, Subra, Karniadakis, George Em
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367819/
https://www.ncbi.nlm.nih.gov/pubmed/28288152
http://dx.doi.org/10.1371/journal.pcbi.1005426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367819/
https://www.ncbi.nlm.nih.gov/pubmed/28288152
http://dx.doi.org/10.1371/journal.pcbi.1005426

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