Cargando…
Patient-specific modeling of individual sickle cell behavior under transient hypoxia
Sickle cell disease (SCD) is a highly complex genetic blood disorder in which red blood cells (RBC) exhibit heterogeneous morphology changes and decreased deformability. We employ a kinetic model for cell morphological sickling that invokes parameters derived from patient-specific data. This model i...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367819/ https://www.ncbi.nlm.nih.gov/pubmed/28288152 http://dx.doi.org/10.1371/journal.pcbi.1005426 |