Epigenetic silencing of V(D)J recombination is a major determinant for selective differentiation of mucosal-associated invariant t cells from induced pluripotent stem cells

Mucosal-associated invariant T cells (MAITs) are innate-like T cells that play a pivotal role in the host defense against infectious diseases, and are also implicated in autoimmune diseases, metabolic diseases, and cancer. Recent studies have shown that induced pluripotent stem cells (iPSCs) derived...

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Detalles Bibliográficos
Autores principales: Saito, Yutaka, Sugimoto, Chie, Mituyama, Toutai, Wakao, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367832/
https://www.ncbi.nlm.nih.gov/pubmed/28346544
http://dx.doi.org/10.1371/journal.pone.0174699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367832/
https://www.ncbi.nlm.nih.gov/pubmed/28346544
http://dx.doi.org/10.1371/journal.pone.0174699

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