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HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes

The first step of HIV infection involves the interaction of the gp120 envelope glycoprotein to its receptor CD4, mainly expressed on CD4(+) T cells. Besides its role on HIV-1 entry, the gp120 has been shown to be involved in the production of IL-1, IL-6, CCL20 and other innate response cytokines by...

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Detalles Bibliográficos
Autores principales: Levast, Benoît, Barblu, Lucie, Coutu, Mathieu, Prévost, Jérémie, Brassard, Nathalie, Peres, Adam, Stegen, Camille, Madrenas, Joaquín, Kaufmann, Daniel E., Finzi, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367833/
https://www.ncbi.nlm.nih.gov/pubmed/28346521
http://dx.doi.org/10.1371/journal.pone.0174550