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Polytopic vaccination with a live-attenuated dengue vaccine enhances B-cell and T-cell activation, but not neutralizing antibodies

Dengue, caused by dengue viruses (DENVs), is the most common arboviral disease of humans. Several dengue vaccine candidates are at different stages of clinical development and one has been licensed. Inoculation with live-attenuated DENV constructs is an approach that has been used by vaccine develop...

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Detalles Bibliográficos
Autores principales: Hunsawong, Taweewun, Wichit, Sineewanlaya, Phonpakobsin, Thipwipha, Poolpanichupatam, Yongyuth, Klungthong, Chonticha, Latthiwongsakorn, Napaporn, Thaisomboonsuk, Butsaya, Im-erbsin, Rawiwan, Yoon, In-Kyu, Ellison, Damon W., Macareo, Louis R., Srikiatkhachorn, Anon, Gibbons, Robert V., Fernandez, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367862/
https://www.ncbi.nlm.nih.gov/pubmed/28393119
http://dx.doi.org/10.1016/j.heliyon.2017.e00271

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