Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation

The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged genes (US12-21) with poorly characterized function. We now identify novel natural killer (NK) cell evasion functions for four members: US12, US14, US18 and US20. Using a systematic multiplexed proteomics approach to q...

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Detalles Bibliográficos
Autores principales: Fielding, Ceri A, Weekes, Michael P, Nobre, Luis V, Ruckova, Eva, Wilkie, Gavin S, Paulo, Joao A, Chang, Chiwen, Suárez, Nicolás M, Davies, James A, Antrobus, Robin, Stanton, Richard J, Aicheler, Rebecca J, Nichols, Hester, Vojtesek, Borek, Trowsdale, John, Davison, Andrew J, Gygi, Steven P, Tomasec, Peter, Lehner, Paul J, Wilkinson, Gavin W G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367895/
https://www.ncbi.nlm.nih.gov/pubmed/28186488
http://dx.doi.org/10.7554/eLife.22206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367895/
https://www.ncbi.nlm.nih.gov/pubmed/28186488
http://dx.doi.org/10.7554/eLife.22206

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